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Laser test to 'spot breast cancer in an instant

New technique will save time and worry for thousands of women
It is hoped that by quickly determining whether a suspicious lump is cancerous, the test will spare women time and worry, as well as cutting the cost for the NHS.
More than 1.5million British women have breast x-rays, or mammograms, each year.
If their result is abnormal, the patient will often have a sample of cells withdrawn via a needle. Up to 90 per cent of these needle biopsies come back negative.
In contrast, a technique developed by the Science and Technologies Facilities Council in Oxfordshire uses a laser to pinpoint dangerous changes without breaking the skin.
Carried out at the same time as the mammogram, the test would remove the need for a second hospital appointment, as well as the nerve-shredding wait for a result.
Nicholas Stone, of the University of Exeter, the project’s lead scientist, said: ‘This technique, if applied at mammography, could have a huge impact on those 75,000 patients a year having to return for biopsies, with associated anxiety, when they are found to have nothing wrong.’
The test involves shining a laser on the suspicious area and analysing the reflected light.
The pattern and colour of the light that is bounced back depends on the chemical composition of the breast – with cancerous lumps producing a different ‘signature’ to benign ones.
Tests on pieces of pork have produced promising results and work on human breast tissue is due to start.
However, the need to prove the test to be highly accurate, as well as safe, means it will be a decade before it is routinely used in hospitals. The laser could also be used in airport security checks to spot liquid explosives and in quality control tests for drugs and medicines.
Scientist Marleen Kerssens, who proved that the so-called Spatially Offset Raman Spectroscopy, or SORS, technique could be used to detect if a lump is malignant or benign, said: ‘It is an exciting field of research and translation of the SORS technique to a clinical setting has the potential to reduce the amount of false positives and therefore reduce patient anxiety.’
Professor Pavel Matousek, who pioneered the technique with the STFC, said: ‘It is very gratifying to see this technology, originally developed on our large facilities, being applied in so many different ways that will have such an impact on society.’
Dr Laura McCallum, of Cancer Research UK, said: ‘If the researchers can prove this technology can tell what is cancer and what’s not, it could save some women from an invasive test and an anxious wait.
‘This is the beginning of a long research journey, but shows how revolutions in technology could help improve medicine in the future.’
Eluned Hughes, of Breakthrough Breast Cancer, said: ‘Accurate diagnosis of breast cancer is crucial so we are encouraged to see the development of new techniques which help identify the disease.
‘We look forward to the results of this study to see how successful the laser technique proves to be.
‘We welcome all research that moves us even closer to providing better diagnosis and treatment for breast cancer patients.’
Women aged between 47 and 73 are entitled to a mammogram every three years, and it is estimated that the screening programme saves 1,400 lives a year. Breast cancer is Britain’s most common form of the disease and almost 50,000 cases are diagnosed each year.
Most are in women aged 50-plus but younger women, and men, are also affected and the disease claims almost 1,000 lives a month.
By Fiona Macrae
Daily Mail, 7 March 2013 - Fly at a Smile-Price